李利华

硕士生导师简介

姓名：李利华                  学历：博士

职称： 副教授                 导师类型：硕导              

招生专业： 生物化学与分子生物学

E-mail：lilihua1976@sicau.edu.cn

个人简介

李利华，男，1976年10月出生于湖北洪湖，理学博士，副教授。2009年6月毕业于华中农业大学作物遗传改良国家重点实验室，同年加入四川农业大学水稻所工作，2010年底晋升为副教授。2013年，加州大学戴维斯分校访学一年，从事拟南芥逆境生理研究。以第一作者或通讯作者在Rice、BMC Plant Biology 、Frontiers in Plant Science等期刊发表SCI论文30余篇。

研究方向

1. 研究水稻在高温、干旱、低温和高盐等非生物逆境下的分子生物学响应及其内在机理。

2. 特色营养功能稻（富硒/彩色/稳糖）新品种创制及功能成因解析。

承担课题

1.四川省教育厅青年基金：一个水稻钙调素结合蛋白基因功能 2010.1-2012.12 （主持）

2.四川省教育厅重点项目：水稻低温诱导基因OsMSI3功能研究，13ZA0249，2013.1-2015.1 (主持)

3.教育部新教师基金：水稻多逆境诱导基因OsMSI1 功能研究，20115103120009，2012.1-2014.12 (主持)

4.四川省科技厅国际合作项目：引进老挝糯稻资源选育富硒红糯米杂交稻， 2017HH0031，2017.1-2019.1 (主持)

5.国家自然科学基金：山兰稻干旱应答基因OsMSI-7 的功能研究，31271802，2013 .1 -2016 .12 (主研)

6.四川省科技厅应用基础重点项目：水稻龙须谷低温诱导基因OsLTI1功能研究，2020YJ0352，2020-01-01 至 2021-12-31（主研）

7.四川省科技厅国际合作项目：富硒水稻硒蛋白提取、纯化及生物活性研究， 2021YFH0085 ，2021.4-2023.3 (主持)

部分学术论文

1. Ziyi Wang, Xiaofei Zan, Hao Chen, Jiali Zhu, Xiulin Zhao, Mingfei Chen, Yijuan Kong, Juan Yang, Xiaomei Jia, Xiaoying Ye, Chuanqiang Liu, Rongjun Chen, Jianqing Zhu, Jun Zhu, Lihua Li*. OsSSID6 Negatively Regulates Salt Stress Tolerance in Rice (Oryza Sativa L.) via Metabolic Pathways and ROS Scavenging. Rice, 2025, 18：111 （1区 TOP）

2. Jiali Zhu, Ziyi Wang, Hao Chen, Mingfei Chen, Xiulin Zhao, Caiyao Mao, Yijuan Kong, Juan Yang, Xiaomei Jia, Xiaoying Ye, Rongjun Chen, Jianqing Zhu, Jun Zhu, Lihua Li*. Overexpression of OsDUF846.2 enhances the sensitivity  of rice to salt and heat stresses. BMC Plant Biology, 2025, 25, 1359（2区 TOP）

3.Hao Chen, Jiale Wan, Jiali Zhu, Ziyi Wang, Caiyao Mao, Wanjing Xu, Juan Yang, Yijuan Kong, Xiaofei Zan, Rongjun Chen, Jianqing Zhu, Zhengjun Xu, Lihua Li*. Overexpression of OsDUF868.12 enhances salt tolerance in rice. Frontiers in Plant Science, 2025, 16, 1458467. （2区 TOP）

4. Miaomiao Lv, Dejia Hou, Jiale Wan, Taozhi Ye, Lin Zhang, Jiangbo Fan, Chunliu Li, Wenqian Chen, Yilun Dong, Songhao Rong, Yihao Sun， Jinghong Xu, Liangjun Cai, Xiaoling Gao, Jianqing Zhu, Zhengjian Huang, Zhengjun Xu, Lihua Li*. OsWRKY97, an Abiotic Stress-Induced Gene of Rice, Plays a Key Role in Drought Tolerance. Plants-Basel, 2023, 12(18), 3338 （2区）

5.Xiaofei Zan, Zhanmei Zhou, Jiale Wan, Hao Chen, Jiali Zhu, Haoran Xu, Jia Zhang, Xiaohong Li, Xiaoling Gao, Rongjun Chen, Zhengjian Huang, Zhengjun Xu*, Lihua Li*. Overexpression of OsHAD3, a Member of HAD Superfamily, Decreases Drought Tolerance of Rice. Rice, 2023，16：31（1区 TOP）

6. Yifan Zhang, Yanmei Yang, Luyi Zhang, Jia Zhang, Zhanmei Zhou, Jinchang Yang, Yu Hu, Xiaoling Gao, Rongjun Chen, Zhengjian Huang, Zhengjun Xu*, Lihua Li*. Antifungal mechanisms of the antagonistic bacterium Bacillus mojavensis UTF-33 and its potential as a new biopesticide. Frontiers in Microbiology, 2023, 14, 1201624 （2区 TOP）

7. Jiale Wan, Jia Zhang, Xiaofei Zan, Jiali Zhu, Hao Chen, Xiaohong Li, Zhanmei Zhou, Xiaoling Gao, Rongjun Chen, Zhengjian Huang, Zhengjun Xu,* Lihua Li*. Overexpression of Rice Histone H1 Gene Reduces Tolerance to Cold and Heat Stress. Plants-Basel, 2023, 12(13), 2048 （2区）

8.Yanmei Yang, Yifan Zhang, Luyi Zhang, Zhanmei Zhou, Jia Zhang, Jinchang Yang, Xiaoling Gao, Rongjun Chen, Zhengjian Huang, Zhengjun Xu*, Lihua Li* Isolation of Bacillus siamensis B-612, a Strain That Is Resistant to Rice Blast Disease and an Investigation of the Mechanisms Responsible for Suppressing Rice Blast Fungus. International Journal of Molecular Sciences, 2023, 24(10), 8513. （2区 TOP）

9.Zhanmei Zhou, Jiangbo Fan, Jia Zhang, Yanmei Yang, Yifan Zhang, Xiaofei Zan, Xiaohong Li, Jiale Wan, Xiaoling Gao, Rongjun Chen, Zhengjian Huang, Zhengjun Xu,* Lihua Li*. OsMLP423 Is a Positive Regulator of Tolerance to Drought and Salt Stresses in Rice. Plants-Basel, 2022, 11(13), 1653（2区）

10. Jia Zhang, Yihao Sun, Zhanmei Zhou, Yifan Zhang, Yanmei Yang, Xiaofei Zan, Xiaohong Li, Jiale Wan, Xiaoling Gao, Rongjun Chen, Zhengjian Huang, Lihua Li*, Zhengjun Xu*. OsSCL30 overexpression reduces the tolerance of rice seedlings to low temperature, drought and salt. Scientific Reports, 2022, 12(1), 8385

11.Zuo Chen, Lu Zhao, Yilun Dong, Wenqian Chen, Chunliu Li, Xiaoling Gao, Rongjun Chen, Lihua Li*, Zhengjun Xu*. The antagonistic mechanism of Bacillus velezensis ZW10 against rice blast disease: Evaluation of ZW10 as a potential biopesticide. PLoS ONE, 2021, 16(8): e0256807

12.Wenqian Chen, Lu Zhao, Hui Li, Yilun Dong, Hong Xu, Ying Guan, Songhao Rong, Xiaoling Gao, Rongjun Chen, Lihua Li*, Zhengjun Xu*. The isolation of the antagonistic strain Bacillus australimaris CQ07 and the exploration of the pathogenic inhibition mechanism of Magnaporthe oryzae. PLOS ONE, 2019, 14 (8): e0220410

13. Hui Li, Ying Guan, Yilun Dong, Lu Zhao, Songhao Rong, Wenqian Chen, Miaomiao Lv, Hong Xu, Xiaoling Gao, Rongjun Chen, Lihua Li*, Zhengjun Xu*. Isolation and evaluation of endophytic Bacillus tequilensis GYLH001 with potential application for biological control of Magnaporthe oryzae. PLOS ONE, 2018 ,13(10): e0203505

14. Lihua Li, Taozhi Ye, Xiaoling Gao, Rongjun Chen, Jinghong Xu, Chen Xie, Jianqing Zhu, Xiaojian Deng, Pingrong Wang, Zhengjun Xu*. Molecular characterization and functional analysis of the OsPsbR gene family in rice. Molecular Genetics and Genomics, 2017, 292:271–281

15.Xiang He^#, Lihua Li^#, Hong Xu, Jiang Xi, Xufeng Cao, Songhao Rong, Yilun Dong, Chuan Wang, Rongjun Chen, Jinghong Xu, Xiaoling Gao, Zhengjun Xu*. A rice jacalin-related mannose-binding lectin gene, OsJRL, enhances Escherichia coli viability under high salinity stress and improves salinity tolerance of rice. Plant Biology (Stuttgart), 2017, 19(2):257-267（并列第一）

16. Lihua Li*, Chao Liu, Xingming Lian. Gene expression profiles in rice roots under low phosphorus stress. Plant Molecular Biology, 2010, 72:423-432.

17. Lihua Li, Xuhua Qiu, Xianghua Li, Shiping Wang, Qifa Zhang, Xingming Lian*. Transcriptomic analysis of rice responses to low phosphorus stress. Chinese Science Bulletin, 2010, 55(3): 251-258（

18. Lihua Li, Xuhua Qiu, Xianghua Li, Shiping Wang, Xingming Lian*. The expression profile of genes in rice roots under low phosphorus stress. Science in China Series C: Life Sciences, 2009, 52(11): 1055-1064

授权专利

1.徐正君，钟凯，李利华等，防治水稻纹枯病和稻瘟病的链霉菌菌株， 专利号：ZL201010028131.2

2.徐正君，姜凯，李利华等，一种防治水稻稻瘟病和纹枯病的芽胞杆菌菌株，专利号：ZL201010028132.7

3.高晓玲，徐正君，李利华等， 从野棉花叶中提取酵母菌抑制剂的方法，专利号：ZL201210246966.4

审定水稻品种

1. 蓉7优46，审定编号：20212030，选育人员：李利华，徐正君，陈荣军，黄正建，徐敬洪。

2. 瑞68优46，审定编号：20242013，选育人员：李利华，徐正君，陈荣军，黄正建，张翅。